Thought Leadership
Project Experience
  • Tereshko V, Teplova M, Brunzelle JS, Watterson DM, Egli M. (2001). Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression. Nature Structural Biology 8(10), 899-907.  1JKL,  1JKK, 1JKS, 1IG1

  • Brunzelle JS, Shafaee JP, Weigand S, Yang X, Ren Z, Anderson WF. (2003). Automated Crystallographic System for High-Throughput Protein Structure Determination. Acta Cryst. D59. 1138-1144.

  • Brunzelle JS, Wu R, Korolev SV, Collart F, Joachimiak A, Anderson WF. (2004) Crystal Structure of Bacillus subtilis ydaF Protein: A Putative Ribosomal N-Acetyltransferase. Proteins: Structure, Function, and Bioinformatics. 57(4), 850-853.

  • Shan L, Vincent J, Brunzelle JS, Dussault I, Lin M, Ianculescu I, Sherman MA, Forman BM, Fernandez E. (2004). Structure of the Murine Constitutive Androstane Receptor Complexed to Androstenol: a Molecular Basis for Inverse Agonism. Molecular Cell. 16, 907-917. 1XNX

  • Wagner JR, Brunzelle JS, Forest KT, Vierstra RD. (2005) A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome. Nature. 438(7066), 325-31. 1ZTU

  • Li B, Yu JP, Brunzelle JS, Moll GN, van der Donk WA, Nair SK. (2006) Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis. Science. 311(5766), 1464-7. 2G02, 2G0D

  • Zhu G, Chen J, Liu J, Brunzelle JS, Huang B, Wakeham N, Terzyan S, Li X, Rao Z, Li G, Zhang XC. (2007) Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J. 26(14), 3484-93. 2Q12, 2Q13

  • Zou Y, Brunzelle JS, Nair SK. (2008) Crystal structures of lipoglycopeptide antibiotic deacetylases: implications for the biosynthesis of A40926 and teicoplanin. Chem. Biol. 15(6), 533-45. 3DFI